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    Home » What We're Eating » Grilled Pork Tenderloin with Spice Rub

    Grilled Pork Tenderloin with Spice Rub

    Published: Apr 29, 2020 by Blair Lonergan

    Jump to Recipe
    Long collage image of Grilled Pork Tenderloin with Spice Rub
    Overhead shot of a blue and white plate with grilled pork tenderloin medallions and a variety of side dishes

    A sweet and zesty barbecue spice rub makes this Grilled Pork Tenderloin a delicious, easy and healthy dinner recipe. The seasoning helps to flavor the meat, caramelize the outside, and yield a juicy tenderloin with a crispy crust. The perfect summer meal!

    Grilled pork tenderloin on a wooden cutting board and basted with barbecue sauce

    Pork tenderloin is a staple in so many of our kitchens because it's an affordable, lean cut of meat that's a nice alternative to chicken. Pork tenderloin cooks quickly, making it ideal for family-friendly, busy weeknight dinners.

    I've been known to prepare pork tenderloin in the slow cooker, but when the weather is warm, nothing beats the smoky char of a grilled pork tenderloin!

    The Difference between Pork Loin and Pork Tenderloin:

    Pork tenderloin, a smaller cut that generally weighs about 1 pound, is not cut from the same part of the animal as the larger pork loin. Since pork tenderloin is naturally lean and tender, it does well when cooked quickly at high temperatures. By contrast, pork loin lends itself well to slower roasting or grilling techniques. For more details about these two different cuts of meat, check out this article.

    Front shot of a plate of grilled pork tenderloin with mac and cheese green beans and coleslaw on the side

    How to make Grilled Pork Tenderloin:

    Grilling is one of the best ways to prepare pork tenderloin (quick cooking at high temperature). To add flavor to the lean meat, we typically use a marinade or dry rub. This particular spice rub uses classic barbecue flavors for a sweet, smoky and savory taste. The dry rub is ideal because it flavors the tenderloin and keeps it moist, without preventing the exterior from getting nice and crispy (as a marinade might).

    Ingredients for a Perfect Grilled Pork Tenderloin Rub:

    • Pork tenderloin
    • Brown sugar
    • Smoked paprika
    • Kosher salt
    • Chili powder
    • Onion powder
    • Garlic powder

    Prepare the Rub:

    First, combine the brown sugar, smoked paprika, kosher salt, chili powder, onion powder and garlic powder in a small bowl. Set aside.

    Spice rub for grilled pork tenderloin

    Season the Meat:

    Next, pat the tenderloin dry and rub the spice mixture all over the meat. Allow the pork to sit at room temperature while you prepare the grill.

    Pork tenderloin on a cutting board coated with spice rub

    Grill the pork tenderloin:

    Preheat an outdoor gas grill or an indoor grill pan to medium heat and brush the grates with vegetable oil (to prevent sticking). Place the pork on the grill, close the grill, and cook for 15-18 minutes. Turn the meat every few minutes to ensure even cooking.

    The pork tenderloin is done when it reaches an internal temperature of 140-145 degrees F. Then remove the meat to a cutting board and allow it to rest for 5-10 minutes before slicing and serving.

    Front shot of a grilled pork tenderloin on a cutting board

    What to serve with Grilled Pork Tenderloin:

    A side of barbecue sauce pairs nicely with the dry rub used on this meat. Serve the grilled pork with any of these easy side dishes, too:

    • Salad dressed in Buttermilk Dressing or Green Goddess Dressing
    • Arkansas Green Beans with Bacon
    • Secret Ingredient Jiffy Cornbread or Pumpkin Muffins
    • Southern Macaroni Salad
    • Coleslaw
    • Southern Collard Greens
    • Crock Pot Mac and Cheese
    • Southern Potato Salad
    • Cowboy Baked Beans

    The best wines to pair with grilled pork tenderloin:

    Since the grilled meat has a smoky-yet-sweet, earthy character, this dish pairs well with wines that have a zippy, refreshing character. You can also opt for a spicy wine that enhances the zesty flavors in the barbecue rub.

    • Pinot Grigio or Pinot Gris
    • Zinfandel
    • Shiraz or Cabernet-Shiraz
    • Rosé
    Close overhead shot of grilled pork tenderloin on a plate with mac and cheese green beans and coleslaw

    Preparation and Storage Tips:

    • Prep ahead! The tenderloin can be trimmed and rubbed up to 24 hours in advance. Remove from the refrigerator 30 minutes before grilling.
    • Store leftovers in an airtight container in the refrigerator for up to 3 days or in the freezer for up to 2 months. Sliced tenderloin is delicious on sandwiches the next day!
    • How to reheat grilled pork tenderloin: Place the pork on a sheet pan and warm in a 325 degree F oven just until heated through (about 10-15 minutes). Be careful not to overheat, or the tenderloin will become dry. You can also reheat individual portions of pork in the microwave for 1-2 minutes.

    Cook's Tips and Recipe Variations:

    • Total grilling time will vary depending on the size, thickness and temperature of your pork and grill. As a result, I always recommend using a meat thermometer to know when your pork is done. The tenderloin is ready to come off the grill when it reaches an internal temperature of 140-145 degrees F. The temperature will continue to rise as it rests, and you want to make sure that you don't overcook the meat (because it can become dry).
    • Barbecue sauce pairs nicely with the dry rub used on the pork. You can baste the tenderloin with barbecue sauce during the final 1-2 minutes of grilling, or you can just serve the grilled pork with a side of warm barbecue sauce for dipping.
    • The salt and sugar are necessary for seasoning the meat and for encouraging caramelization on the outside. You can adjust the other spices to suit your taste. For instance, substitute regular paprika for the smoked paprika, or add a dash of cayenne for a spicy rub.
    • A single pork tenderloin is typically just 1 lb. of meat, making it an appropriate amount of food for 2-4 people (depending on the size of your appetite). If you're feeding a larger family of 4-5, I recommend doubling all of the ingredients and cooking two tenderloins side-by-side on the grill.
    • Pork tenderloin is a healthy option for most diets. The extra-lean meat is high in protein and a rich source of B vitamins and selenium. One 4-ounce serving of pork tenderloin has almost 24 grams of protein, 0 carbohydrates, less than 4 grams of fat, and just 136 calories. The American Heart Association has certified pork tenderloin as a heart healthy food!
    Close up front shot of sliced grilled pork tenderloin with rub on a plate

    More grilled pork tenderloin recipes that you might enjoy:

    • Honey Garlic Dijon Pork Tenderloin Marinade
    • Pork Tenderloin with Zucchini and Corn
    • Garlic and Herb Grilled Pork Tenderloin Kabobs
    • Pork Tenderloin Marinade for the Grill
    Grilled pork tenderloin on a wooden cutting board and basted with barbecue sauce
    Print Pin
    5 from 2 votes

    Grilled Pork Tenderloin with Spice Rub

    Grilled pork tenderloin with a sweet-and-smoky barbecue rub is a healthy and easy dinner recipe that's perfect for spring and summer!
    Course Dinner
    Cuisine American
    Keyword Grilled Pork Tenderloin, grilled pork tenderloin rub
    Prep Time 15 minutes
    Cook Time 18 minutes
    Resting Time 15 minutes
    Total Time 48 minutes
    Servings 2 - 4 people
    Calories 228.3kcal
    Author Blair Lonergan

    Ingredients

    • 1 pork tenderloin (about 1 lb.)
    • 2 tablespoons brown sugar
    • 2 teaspoons smoked paprika
    • 1 ½ teaspoons kosher salt
    • 1 teaspoon chili powder
    • 1 teaspoon onion powder
    • 1 teaspoon garlic powder
    • Optional, for serving: barbecue sauce

    Instructions

    • In a small bowl, combine brown sugar, smoked paprika, kosher salt, chili powder, onion powder and garlic powder.
    • Trim the pork tenderloin of any excess fat and silverskin. Pat the pork dry, and then rub the spice mixture all over the meat.
    • Allow pork to sit at room temperature while preparing the grill.
    • Preheat grill to medium heat and brush the grates with vegetable oil (to prevent sticking).
    • Place pork on the grill. Close the grill and cook 15-18 minutes, turning every few minutes to ensure even cooking. The meat is done when it reaches an internal temperature of 140-145 degrees F. You can baste with the barbecue sauce during the final 1-2 minutes, or just serve warm barbecue sauce alongside the pork for dipping.
    • Remove the tenderloin to a cutting board and allow the meat to rest for about 5-10 minutes before slicing and serving.

    Notes

    • Total grilling time will vary depending on the size, thickness and temperature of your pork and grill. As a result, I always recommend using a meat thermometer to know when your pork is done. The tenderloin is ready to come off the grill when it reaches an internal temperature of 140-145 degrees F. The temperature will continue to rise as it rests, and you want to make sure that you don't overcook the meat (because it can become dry).
    • Barbecue sauce pairs nicely with the dry rub used on the pork. You can baste the tenderloin with barbecue sauce during the final 1-2 minutes of grilling, or you can just serve the grilled pork with a side of warm barbecue sauce for dipping.
    • The salt and sugar are necessary for seasoning the meat and for encouraging caramelization on the outside. You can adjust the other spices to suit your taste. For instance, substitute regular paprika for the smoked paprika, or add a dash of cayenne for a spicy rub.
    • A single pork tenderloin is typically just 1 lb. of meat, making it an appropriate amount of food for 2-4 people (depending on the size of your appetite). If you're feeding a larger family of 4-5, I recommend doubling all of the ingredients and cooking two tenderloins side-by-side on the grill.
    • Pork tenderloin is a healthy option for most diets. The extra-lean meat is high in protein and a rich source of B vitamins and selenium. One 4-ounce serving of pork tenderloin has almost 24 grams of protein, 0 carbohydrates, less than 4 grams of fat, and just 136 calories. The American Heart Association has certified pork tenderloin as a heart healthy food!

    Nutrition

    Serving: 1/3 of the tenderloin | Calories: 228.3kcal | Carbohydrates: 14.8g | Protein: 32.1g | Fat: 5.5g | Saturated Fat: 1.8g | Polyunsaturated Fat: 0.2g | Cholesterol: 97.3mg | Sodium: 649.5mg | Potassium: 649.7mg | Fiber: 1g | Sugar: 9.2g
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    Reader Interactions

    Comments

    1. Lois J Moore

      June 28, 2020 at 9:18 am

      Have a nice port tenderloin, waiting for a new rub. This one looks really good. Thank you for sharing.

      Reply
      • Blair

        June 28, 2020 at 12:31 pm

        Perfect, Lois! This is our very favorite way to prepare grilled pork tenderloin. 🙂

        Reply
    2. Lorraine Lorentz

      August 16, 2020 at 8:43 pm

      5 stars
      Made this tonight and probably my favorite tenderloin recipe yet! Quick, delicious, and not alot of room for error. Just wish I would have thought to make the mac and cheese too!Thanks Blair!

      Reply
      • Blair

        August 17, 2020 at 5:50 am

        That's amazing! I'm so glad that you enjoyed it, Lorraine! 🙂

        Reply
    3. Lori

      February 01, 2021 at 6:33 pm

      5 stars
      This rub was outstanding. My family loved it. I am going to try it on ribs and chicken.

      Reply
      • Blair

        February 01, 2021 at 7:42 pm

        It's so delicious on ribs and chicken, too. I'm glad that you enjoyed it, Lori. Thanks for your note!

        Reply
    4. Val

      July 02, 2021 at 3:28 pm

      Is this rub good if baked in oven too?

      Reply
      • Blair

        July 02, 2021 at 3:45 pm

        Yes, it is! 🙂

        Reply
        • Val

          July 02, 2021 at 4:02 pm

          Will try it tonight!

          Reply

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