Preheat oven to 450 degrees F.
Place salmon in a greased 9 x 13-inch baking dish or on a parchment-lined rimmed baking sheet. Pat salmon dry with paper towels and season liberally with salt and pepper.
4 salmon fillets (6 ounces each)
In a medium bowl, whisk together soy sauce, honey, orange juice, Worcestershire sauce, and garlic powder.
2 Tablespoons soy sauce, 2 Tablespoons honey, 1 Tablespoon orange juice, 1 teaspoon Worcestershire sauce, 1 teaspoon garlic powder
Brush soy sauce over the fish. Reserve remaining soy sauce mixture for basting.
Roast salmon in the 450 degree F oven for 10-12 minutes, or until fish flakes easily with a fork. Baste with additional sauce halfway through the baking time.