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Square overhead shot of sliced Southern meatloaf on a platter.
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5 from 7 votes

Southern Meatloaf

This Southern meatloaf recipe uses cornbread crumbs and a blend of ground beef and pork for a moist, flavorful twist on the classic. The ketchup-Worcestershire glaze adds a sweet and savory finish that the whole family will love.
Course Dinner
Cuisine American, Southern
Keyword best meatloaf recipe, easy meatloaf recipe, southern meatloaf recipe
Prep Time 20 minutes
Cook Time 1 hour
Resting Time 10 minutes
Total Time 1 hour 30 minutes
Servings 6 people
Calories 443kcal

Equipment

  • Rimmed baking sheet

Ingredients

  • ¾ cup ketchup
  • 2 tablespoons Worcestershire sauce
  • 1 lb. lean ground beef
  • 1 lb. ground pork
  • 1 cup day old (very stale/dry) cornbread crumbs (or other fresh breadcrumbs)
  • 1 small onion, grated or finely diced
  • 2 large eggs, lightly beaten
  • 1 tablespoon dried basil (or about ¼ cup chopped fresh basil)
  • 1 tablespoon Dijon mustard
  • 2 cloves garlic, grated or minced (about 2 teaspoons)
  • 2 teaspoons kosher salt
  • 1 teaspoon dried oregano
  • ½ teaspoon ground black pepper
  • Optional, for serving: mashed potatoes, chopped fresh herbs for garnish

Instructions

  • Preheat oven to 375°F. Line a rimmed baking sheet with parchment paper and set aside.
  • In a small bowl, stir together ketchup and Worcestershire sauce. Set aside.
    Ketchup mixture for a Southern meatloaf recipe.
  • In a large bowl, use your hands or a fork to gently combine beef, pork, cornbread crumbs, onion, eggs, basil, Dijon, garlic, salt, oregano, pepper, and ½ cup of the ketchup mixture. Mix until just combined. Be careful not to overmix or the meatloaf will be dense.
    Southern meatloaf mixture in a bowl.
  • On the prepared baking sheet, shape the meat mixture into a rectangular loaf.
    Shaping meatloaf on a baking sheet.
  • Spread the remaining ketchup mixture evenly over the top.
    Spreading the ketchup glaze on top of a Southern meatloaf before baking.
  • Bake for about 1 hour, until the internal temperature reaches 160°F and the meatloaf is cooked through.
  • Remove from the oven and let rest for 5-10 minutes before slicing. Serve warm with mashed potatoes and fresh herbs if desired.
    Horizontal side shot of Southern meatloaf on a table with a side of cornbread, mashed potatoes, and broccoli.

Video

Notes

  • Don't overmix. Use your hands or a fork to gently combine everything. Overworking makes the meatloaf dense and mushy.
  • Use lean ground beef (85%-93% lean). You need some fat for moisture, but too much makes it greasy.
  • No need to cover the meatloaf while baking.
  • Check for doneness with an instant-read thermometer. It's done at 160°F when the juices run clear.
  • Prevent cracking by placing a pan of hot water on the rack below the meatloaf.
  • Let it rest for 5-10 minutes before slicing. This helps it hold together.
  • Loaf pan option: Bake in a greased 9x5-inch loaf pan. Tilt to drain grease at the end.
  • Cornbread substitutes: Use fresh breadcrumbs or cracker crumbs (like saltines) if you don't have cornbread.
  • Mustard swap: Yellow mustard works in place of Dijon.
  • Herb variations: Try rosemary, chives, parsley, or thyme in addition to basil and oregano.
  • Add vegetables: Diced bell pepper, grated zucchini, celery, or carrots are great additions. Sauté first for softer texture.
  • Meat options: Use all ground beef, some ground turkey, or a "meatloaf mix" of beef, pork, and veal.
  • Add cheese: A handful of grated cheddar mixed in is delicious!
Recipe adapted from Sarah Foster's book, Southern Kitchen.

Nutrition

Serving: 1slice | Calories: 443kcal | Carbohydrates: 25g | Protein: 34g | Fat: 23g | Saturated Fat: 8g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 10g | Trans Fat: 0.3g | Cholesterol: 163mg | Sodium: 1397mg | Potassium: 715mg | Fiber: 2g | Sugar: 9g | Vitamin A: 267IU | Vitamin C: 4mg | Calcium: 98mg | Iron: 5mg