Preheat the oven to 375°F. Line a rimmed baking sheet with parchment paper; set aside (or grease a 9 x 5-inch loaf pan if you prefer). In a small bowl, stir together the bbq sauce and Worcestershire sauce. Set aside.
In a large bowl, use your hands or a fork to gently combine the ground beef, cornbread crumbs, onion, eggs, parsley, Dijon, garlic, salt, oregano, pepper, and ½ cup of the bbq sauce mixture. Be careful not to mash or over-mix or the meatloaf will be dense or mushy.
On the prepared baking sheet, shape the meat mixture into a rectangular loaf (or pat the meat into the greased loaf pan). Spread the remaining bbq sauce mixture on top.
Bake the meatloaf for about 1 hour, or until the internal temperature is 160°F and the meatloaf is cooked through. (A pan of hot water in the oven, under the meatloaf, will prevent the top from cracking.) Remove from the oven and let rest for 5-10 minutes before slicing. Serve warm.