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5 from 1 vote

Overnight Southern Biscuit, Ham and Egg Bake

An overnight egg bake with biscuits and ham. Toss the ingredients together the night before then bake it for 10 minutes in the morning.
Course Breakfast
Cuisine American
Keyword egg bake with biscuits, egg bake with ham
Prep Time 10 minutes
Cook Time 45 minutes
Total Time 55 minutes
Servings 8 servings
Calories 405kcal
Author The Seasoned Mom


  • 10.6 ounces about 2 cups diced ham
  • 8 biscuits cooked, cooled, and cubed (about 8 cups total)*
  • 2 cups 8 ounces shredded cheddar cheese
  • cup chopped scallions
  • 1 jar 4 ounces diced pimientos, drained
  • 1 teaspoon salt
  • ½ teaspoon pepper
  • 8 large eggs
  • 2 cups whole milk
  • Pinch of grated nutmeg
  • Fresh herbs for garnish


  • Spray a 9x13-inch baking dish with cooking spray and set aside.
  • In a large bowl, stir together ham, cubed biscuits, cheese, scallions, pimientos, ½ teaspoon of salt, and ¼ teaspoon of pepper. Transfer to the prepared baking dish.
  • In a large bowl, whisk together eggs, milk, nutmeg, remaining ½ teaspoon of salt and remaining ¼ teaspoon of pepper. Pour the egg mixture over the biscuit mixture. Use your hands or a spoon to gently combine the biscuits with the eggs to make sure that everything is nicely coated. You want the biscuits to absorb the liquid.
  • Cover casserole and refrigerate for at least one hour (or up to overnight).
  • Before baking, allow the casserole to sit on the counter and come to room temperature for about 20 minutes while you preheat the oven.
  • If the casserole has been sitting overnight, I like to give everything a gentle stir in the dish to make sure that all of the biscuits are coated with the egg mixture before it goes in the oven.
  • Preheat the oven to 350°F/180°C.
  • Bake, uncovered, for 45-50 minutes (until eggs are set and top is golden brown). Garnish with fresh herbs just before serving.


*I used a 16-ounce can of refrigerated Immaculate brand Organic Flaky Biscuits.


Calories: 405kcal | Carbohydrates: 17g | Protein: 24g | Fat: 26g | Saturated Fat: 11g | Cholesterol: 223mg | Sodium: 1256mg | Potassium: 348mg | Sugar: 4g | Vitamin A: 660IU | Vitamin C: 0.7mg | Calcium: 316mg | Iron: 2.3mg