5 from 2 votes
Close front shot of cheeseburger casserole in a blue and white bowl
Cheeseburger Casserole
Prep Time
20 mins
Cook Time
20 mins
Total Time
40 mins

You only need about 20 minutes to assemble a Cheeseburger Casserole that your whole family will adore!

Course: Dinner
Cuisine: American
Keyword: cheeseburger casserole, ground beef casserole
Servings: 6 - 8 people
Calories: 397.7 kcal
Author: Blair
  • 2 cups uncooked rotini pasta (about 5 ounces)
  • 1 lb. ground beef
  • ½ cup chopped onion
  • 2 teaspoons minced fresh garlic
  • 1 (10.75 oz) can condensed cheddar cheese soup, NOT diluted
  • ½ cup milk
  • 1 (14.5 oz) can petite diced tomatoes, drained
  • ¼ cup sweet pickle relish
  • 2 tablespoons yellow mustard
  • 2 tablespoons ketchup
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon kosher salt
  • ½ teaspoon black pepper
  • 2 cups (8 ounces) grated cheddar cheese, divided
  • Optional garnish: sliced green onion, chopped or sliced dill pickles, chopped fresh parsley
  1. Preheat oven to 350 degrees F. Spray a 2-quart baking dish with cooking spray. Set aside.
  2. Cook pasta in salted water until al dente, according to package instructions (about 8-10 minutes). Drain.
  3. While the pasta cooks, brown beef, onion and garlic in a large skillet over medium-high heat until meat is no longer pink. Drain. Stir in condensed soup, milk, tomatoes, pickle relish, mustard, ketchup, Worcestershire sauce, salt, pepper, 1 cup of cheese, and cooked pasta.
  4. Transfer mixture to the prepared baking dish. Sprinkle remaining 1 cup cheese over top. Bake for 15-20 minutes, or until cheese is melted and casserole is heated through.
  5. Garnish with sliced green onions, dill pickle, or fresh herbs, if desired.
Recipe Notes
Nutrition Facts
Cheeseburger Casserole
Amount Per Serving (1 /8 of the casserole)
Calories 397.7 Calories from Fat 184
% Daily Value*
Fat 20.4g31%
Saturated Fat 10.2g64%
Polyunsaturated Fat 0.8g
Monounsaturated Fat 6.6g
Cholesterol 84.7mg28%
Sodium 1088.2mg47%
Potassium 309.2mg9%
Carbohydrates 25.8g9%
Fiber 2.2g9%
Sugar 6.7g7%
Protein 27.1g54%
* Percent Daily Values are based on a 2000 calorie diet.