Preheat oven to BROIL on HIGH and place a rack about 5-6 inches from the broiler unit. Line a rimmed baking sheet with foil and spray with non-stick cooking spray. Set aside.
Pat tilapia dry and season with salt and pepper, to taste.
Combine melted butter, lemon juice, and garlic powder in a small bowl. Brush the butter mixture on both sides of the fish.
Place the fish on the prepared baking sheet, bottom side UP, and broil for 5 minutes. Flip the fish over, sprinkle with Parmesan cheese, and return to the broiler for 5-6 more minutes. The fish will flake easily with a fork when it’s done.
Garnish with lemon wedges and parsley.
Video
Notes
How to cook frozen tilapia: If you're starting with frozen tilapia, thaw the fish in the refrigerator overnight. Pat dry with paper towels and use in the recipe as instructed.
Broil the tilapia about 5-6 inches from the heat. Always keep a close eye on food when it's under the broiler, as it can burn very quickly.
Serving sizes: This recipe yields four very large servings. If you're cooking for two, or if you have smaller appetites to feed, I would suggest using only two or three tilapia fillets.
Garnish each serving with fresh herbs, such as parsley, basil, or chives, a lemon wedge, or a squeeze of fresh lemon juice. You can also sprinkle with red pepper flakes for some heat!